stehlik-dorfleutner lab publications 2001-2005

Damiano JS, Stehlik C, Pio F, Godzik A, Reed JC. CLAN, a novel human CED-4-like gene. Genomics 2001, 75, p77-83. PMID:11472070  |  pdf

Lee SH, Stehlik C, Reed JC. Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing. Journal of Biological Chemistry 2001, 276, p34495-34500. PMID:11432859  |  pdf

Stehlik C, Fiorentino L, Dorfleutner A, Bruey JM, Ariza EM, Sagara J, Reed JC. The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways. Journal of Experimental Medicine 2002, 196, p1605-615. PMID:12486103  |  pdf

Fiorentino L, Stehlik C, Oliveira V, Ariza ME, Godzik A, Reed JC. A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumornecrosis factor-alpha and interleukin-1beta. Journal of Biological Chemistry 2002, 277, p35333-35340. PMID:12093792  |  pdf

Stehlik C, Lee SH, Dorfleutner A, Stassinopoulos A, Sagara J, Reed JC. Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation. Journal of Immunology 2003, 171, p6154-6163. PMID:14634131  |  pdf

Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A; RIKEN GER Group.; GSL Members. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Research 2003, 13, p1376-1388. PMID:12819136  |  pdf

Stehlik C, Hayashi H, Pio F, Godzik A, Reed JC. CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways. Journal of Biological Chemistry 2003, 278, p31941-31949. PMID:12775719  | pdf

Stehlik C, Krajewska M, Welsh K, Krajewski S, Godzik A, Reed JC. The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation. Biochemical Journal 2003, 373, p101-113. PMID:12656673  |pdf    |   editorial: Mariathasan, S and Vucic, D. POPing the fire into pyrin? Biochemical Journal 2003, 373, e1-e2  | pdf

Dorfleutner A, Ruf W. Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation. Blood 2003, 102, p3998-4005. PMID:12920028  |   pdf

Ruf W, Dorfleutner A, Riewald M. Specificity of coagulation factor signaling. Journal of Thrombosis and Haemostasis 2003, 1, p1495-1503. PMID:12871285  |  pdf

Belting M, Dorrell M, Sandgren S, Aguilar E, Ahamed J, Dorfleutner A, Carmeliet P, Mueller B, Friedlander M, Ruf W. (2004) Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nature Medicine 2004, 10, p502-509. PMID:15098027   |   pdf

Kroismayr R, Baranyi U, Stehlik C, Dorfleutner A, Binder BR, Lipp J. HERC5, a HECT E3 ubiquitin ligase lightly regulated in LPS activated endothelial cells. Journal of Cell Sciences 2004,117, p4749-4756. PMID:15331633   |  pdf

Stehlik C, Kroismayr R, Dorfleutner A, Binder BR, Lipp J. VIGR – a novel inducible adhesion family G-protein coupled receptor in endothelial cells. FEBS Letters 2004, 569, p149-155. PMID:15225624  |  pdf

Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Stehlik C, Reed JC. PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages. Journal of Biological Chemistry 2004, 279, p51897-51907. PMID:15456791   |   pdf

Stehlik C, Reed JC. The PYRIN connection: novel players in innate immunity and inflammation. Journal of Experimental Medicine 2004, 200, p551-558. PMID:15353551  |   pdf

Medan D, Wang L, Toledo D, Lu B, Stehlik C, Jiang BH, Shi X, Rojanasakul Y. Regulation of Fas (CD95)-induced apoptotic and necrotic cell death by reactive oxygen species in macrophages. Journal of Cellular Physiology 2005, 203, p78-84. PMID:1536854  |  pdf

Chanvorachote P, Nimmannit U, Wang L, Stehlik C, Lu B, Azad N, Rojanasakul Y.Nitric oxide negatively regulates Fas CD95-induced apoptosis through inhibition of ubiquitin-proteasome-mediated degradation of FLICE inhibitory protein. Journal of Biological Chemistry 2005, 280, p42044-42050. PMID:16246840  |  pdf